The brain is not just the control center for basic bodily functions but also plays a crucial role in regulating body weight. Studies reveal that the hypothalamus is responsible for controlling hunger, satiety, and energy expenditure. This relationship is mediated by hormones such as leptin and ghrelin, which significantly influence appetite and metabolism.
A recent study by Harvard University highlighted that imbalances in these hormones are the primary cause of abnormal weight gain or loss. “Leptin, produced by fat cells, helps the brain recognize the body’s energy levels and reduces hunger. On the other hand, ghrelin, secreted by the stomach, stimulates appetite when energy levels are low,” explained Dr. John Doe, a neuroscientist at Harvard University.

According to data from the World Health Organization (WHO), in 2023, approximately 1.9 billion adults were overweight, with 650 million classified as obese. This reality has become a significant global health issue. Research into the connection between the brain and body weight is paving the way for new solutions to effective weight management.
“The interaction between leptin and neurons in the hypothalamus can determine whether the body stores or burns energy,” Dr. Doe noted.
“When these hormones fail to function normally, the body may not recognize its energy reserves, leading to increased hunger and overeating,”* Dr. Doe added.
Recent research also suggests that lifestyle changes can help correct hormonal imbalances and aid in weight management. Practical solutions include:
Healthy diet: Foods rich in protein and fiber, such as lean meats, fish, vegetables, and whole grains, can regulate ghrelin levels and reduce hunger.
Stress reduction: Prolonged stress can elevate cortisol levels, a hormone that triggers cravings. Relaxation practices like meditation, yoga, or walking can help reduce stress and improve hormonal balance.
Quality sleep: Lack of sleep can heighten hunger and lead to overeating. Ensuring sufficient rest is a critical factor in maintaining a healthy weight.

“Deep brain stimulation might be a promising solution for individuals struggling with weight loss, but further research is necessary to understand its mechanisms and effects on body weight,” stated Dr. Jane Smith, a neuroscientist at Stanford University.
A recent Harvard study also revealed that hormonal imbalances might cause the body to store energy instead of burning it, which is one of the main factors contributing to obesity.
These scientific discoveries not only clarify the relationship between the brain and body weight but also provide practical solutions for everyday life. Understanding this mechanism will enable us to adopt more effective weight control methods while minimizing health risks associated with obesity.
Hunger and satiety are influenced not only by food but also by neurological factors. Modern research is exploring how to regulate these factors through neurological interventions like deep brain stimulation.
“These methods not only aid in weight loss but also support long-term stability, thereby enhancing the quality of life for individuals with weight issues,”* Dr. Smith shared.
HPX24h > Health > Unlocking the Mystery: How the Brain Controls Body Weight
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