Recently, a team of researchers at University of Queensland has decoded one of the long-standing mysteries of the human brain: how it manages emotions and stores memories. The latest research shows that there are at least two distinct types of stem cells in the hippocampus – a region crucial for learning and memory. Previously, scientists believed that the stem cells in this region were homogeneous, but this new discovery indicates that each type of stem cell has a specific role, helping explain why the hippocampus can regulate both emotions and learning.
“Previously, we thought that all the stem cells in the hippocampus were the same. However, the new study reveals the existence of two different types of stem cells, each performing distinct functions,” said the research team from University of Queensland. This discovery not only helps scientists better understand how the brain functions, but also opens up opportunities for treating memory and mood-related disorders. (Source: University of Queensland, published in Nature Neuroscience, 2023)

The hippocampus, a region of the brain, plays a key role in memory formation and emotion regulation. By analyzing the stem cells in this area, the research team discovered that these cells develop into neurons with different characteristics, allowing the brain to coordinate both of these important functions. Understanding this mechanism could lead to significant applications in the treatment of psychological disorders such as depression, anxiety, and dementia.
“We discovered that new memories create unique activity patterns in the brain, which help us identify the thoughts or ideas the participants are thinking about. This is a major step forward in understanding how the brain stores and processes information,” according to the research team (Source: University of Queensland, published in Science Advances, 2023).
One of the notable findings of the study is the difference in the “signatures” of concepts related to animals with similar habitats. Species with similar characteristics (such as their environment) produce very similar brain activity “signatures.” This shows that the brain has the ability to categorize and link information based on shared traits, improving its ability to organize and store memories.
“We were able to read the thoughts of the participants simply by tracking their brain activity patterns. These activity signatures allowed us to know exactly which animal they were thinking about, and this could help us understand how the brain connects new information with old information,” the research team emphasized (Source: University of Queensland, published in Neuron, 2023).

This discovery provides a new perspective on the mechanisms of memory storage and emotion regulation in the brain. These findings not only help scientists better understand how the brain processes information but also open new prospects for treating memory and mood-related disorders. Understanding the classification of stem cells could help develop more effective therapies for conditions such as depression and anxiety.
This is an important advancement in neuroscience, unlocking potential treatments for complex neurological disorders and offering deep insights into how the brain controls essential aspects of human life, such as emotions and memory.
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